Xizhan Huang

Senescent cancer-associated fibroblasts secrete Tenascin-C to promote tumor progression in high-grade serous ovarian cancer

Cellular senescence is a hallmark of cancer, and senescent cancer-associated fibroblasts (seneCAFs) contribute to tumor progression across multiple malignancies. However, how seneCAFs promote high-grade serous ovarian (HGSOC) remains unclear. We integrated public single-cell RNA...