Xixi Tan

Mutations in EnvZ, KPC, and OmpK36 contribute to the evolution from ceftazidime-avibactam heteroresistance to stable resistance in carbapenem-resistant Klebsiella pneumoniae

Antibiotic heteroresistance, an unstable phenotype wherein a minority-resistant subpopulation coexists with a majority-susceptible population, can evolve to stable resistance following in vivo antibiotic exposure, thereby substantially increasing the risk of treatment failure. Ho...

A Clinically Accessible Nomogram for Identifying Likely Psoriatic Arthritis Among Patients with Psoriasis: A Multicenter Cross-Sectional Study

Background/Objectives: Psoriatic arthritis (PsA) affects up to 30% of psoriasis patients but remains underdiagnosed due to heterogeneous early manifestations. Existing tools rely on advanced imaging or biomarkers, limiting feasibility. This study aimed to develop a simple nomogra...