Xiumin Wang

A novel medical image segmentation network for colorectal polyp small targets and fuzzy boundaries

OBJECTIVES: To address the challenges of complex feature variations and unclear boundary definitions between segmented targets and surrounding regions in medical images, a novel segmentation model based on Deformable Large Kernel Convolutional Attention (D-LKA) and Transformer is...

Systemic metabolic remodeling in mucopolysaccharidosis revealed by untargeted urinary metabolomics

Abstract Background Mucopolysaccharidoses (MPS) are lysosomal storage disorders characterized by glycosaminoglycan (GAG) accumulation and progressive multi-organ dysfunction. However, the systemic metabolic consequences of lysosomal dysfunction remain incompletely defined. Method...