Xinzhen Yu

Benchmarking of pathology foundation models for assessing HER2 amplification and CEP17 polysomy in breast cancer

Abstract Accurate assessment of Human Epidermal Growth Factor Receptor 2 (HER2) amplification and Chromosome 17 (CEP17) copy number is critical for breast cancer treatment, yet diagnostically equivocal (IHC 2+) cases remain a clinical bottleneck. This study systematically benchma...