Xinyu He

Wnt2bb-triggered neighbor cell proliferation is essential for cloaca formation by inducing apoptosis in the cloaca through cell competition

Cloaca serves as the only opening for the digestive, urinary, and reproductive tracts in multiple species. Apoptosis is crucial for shaping the cloaca, yet the underlying mechanisms remain largely unclarified. Here we find that Wnt2bb-triggered neighbor cell proliferation is esse...