Xinyi Shi

Glycosides from Cistanche tubulosa suppress intestinal ACSL4-mediated ferroptosis to ameliorate depression with intestinal dysfunction symptoms through regulating arachidonic acid metabolism

Abstract Background Depression is highly comorbid with intestinal dysfunction, yet antidepressant therapies are limited by suboptimal efficacy and frequent gastrointestinal adverse effects. Existing cellular and animal data support the potentially dual protective effects of total...