Xinyi Fang

RAB18-dependent recruitment of OPTN initiates selective lipophagy in osteoblasts

Selective lipophagy requires cargo recognition and recruitment of autophagy receptors to lipid droplets (LDs), yet the molecular mechanisms that couple LDs to the core autophagy machinery remain poorly defined. Here, we identified the small GTPase RAB18 (RAB18, member RAS oncogen...