Xingyu Chen

Rational Nanomaterial Design for Ferroptosis Modulation: Bidirectional Therapeutic Strategies in Cancer and Beyond

Abstract Ferroptosis, a unique form of regulated, iron-dependent cell death, has emerged as a therapeutic mechanism for a range of diseases, including cancer, neurodegeneration, metabolic disorders, and organ injuries. However, the clinical translation of small-molecule ferroptos...

Environmentally Responsive Catalytic Microneedles Enable Cascade Fenton Reaction for Antibacterial Therapy and Accelerated Infected Wound Healing

ABSTRACT The persistence of bacterial biofilms and resistance limits the efficacy of traditional therapies, slowing tissue regeneration. Here, we report an innovative pH‐responsive catalytic microneedle system (GZIF@Fe MN) designed to combat bacterial infections by disrupting bac...