Xingqiang Lai

Targeting IRE1α/XBP1 signaling synergizes with cyclosporine A to ameliorate skin allograft rejection

Abstract This study investigated the synergistic effect and immunomodulatory mechanism of combining IRE1α/XBP1 pathway inhibition with cyclosporine A (CsA) against acute rejection in a murine allogeneic skin transplant model. BALB/c-to-C57BL/6 skin allograft recipients were treat...