Xingdong Chen

Selection and prediction of targeted serum protein biomarkers for early diagnosis of esophageal squamous cell carcinoma

Achieving early diagnosis of esophageal squamous cell carcinoma (ESCC) is crucial for reducing the disease burden. This study aims to identify potential serum protein biomarkers associated with the early diagnosis of ESCC in two independent populations and further develop diagnos...

Galectin-3 worsens microglia-mediated synaptic engulfment and neuroinflammatory responses after traumatic brain injury

Activated microglia-mediated aberrant synaptic phagocytosis is an important contributor to neurological deficits following traumatic brain injury (TBI). Galectin-3 (Gal-3), a pivotal regulator of microglial activity, is increased after TBI. However, its role in microglia-mediated...