Xifeng Chang

Myf5 Progenitors Define the Lineage Identity of Somitic Vascular Smooth Muscle Cells

Vascular smooth muscle cell (VSMC) heterogeneity drives region-specific aortic pathologies, yet the roles of somite-derived lineages remain unclear. Utilizing Myf5 and MyoD lineage tracing alongside a smooth muscle-specific Myf5 conditional knockout model, we show that Myf5-deriv...