Xiaoyuan Shawn Chen

Ultrasound-activatable bacteria for biomedical applications

Bacteria have emerged as powerful therapeutic vectors owing to their intrinsic tumour tropism, genetic programmability, and living therapeutic functions. However, the trade-off between their autonomous proliferation and potential immunotoxicity restricts their clinical translatio...

Targeting FibroblastActivation Protein for PrecisionMedicine

Conspectus The advancement of precision medicine depends critically on well-defined molecular targets. Pathologically activated fibroblasts drive disease progression in cancer, fibrosis and chronic inflammation through sustained inflammation, extracellular matrix remodeling and p...