Xiaorong Yang

The SIRT1-ΔExon8 transcript is differentially expressed across brain regions and during neural stem cell differentiation in rats

SIRT1 is an NAD+-dependent deacetylase involved in the maintenance and differentiation of neural stem cells (NSCs). Although alternative splicing increases the regulatory complexity of SIRT1, its splice isoforms in the rat nervous system remain poorly defined. This study aimed to...