xiaoqun ye

PNA-TPP treatment is associated with Drp1-related mitochondrial dysfunction and an enhanced response to cisplatin in A549-derived stem-like spheres

Cisplatin (CDDP) resistance reduces the treatment effect in non-small cell lung cancer. Lung cancer stem-like cells are closely linked to drug tolerance. Mitochondrial dysfunction may affect their stemness and response to treatment. This study examined whether peptide nucleic aci...