Author
Xiaodong Shi
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Recent research
- Materials & Energy
Construction of Quinoline-4-carboxylic Acids via DNA-Compatible Doebner Reaction
Abstract The Doebner reaction is a classical method for the synthesis of quinoline-4-carboxylic acids via the condensation of anilines, aldehydes, and pyruvic acid. However, its application in DNA-encoded library (DEL) technology has been limited due to harsh reaction conditions...