Xiaobing Ju

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

ABSTRACT Renal allograft interstitial fibrosis/tubular atrophy (IF/TA) is the pathological hallmark of chronic renal allograft dysfunction (CAD) and endothelial‐to‐mesenchymal transition (EndMT) has been implicated as one of the key triggering factors. Here, we identified tumor n...

Transcriptomic and histological analyses reveal immune dysregulation in BK virus-associated nephropathy

Abstract BK virus-associated nephropathy (BKVN) is an important cause of kidney allograft failure and involves complex immune responses. This study aimed to characterize gene expression changes and immune microenvironment features in BKVN tissues using transcriptomic analysis. Us...