Xianwen Wang

Identification of annexin A10 as a candidate serum biomarker associated with neurological outcome after cardiac arrest

Accurate early neurological prognostication following cardiac arrest remains a major clinical challenge because of post-resuscitation brain injury. Although biomarkers such as neuron-specific enolase (NSE) and neurofilament light chain (NfL) are widely investigated, limitations i...

Immune-inflammatory biomarkers for in-hospital mortality risk stratification in older patients with sepsis: a multicentre leave-one-hospital-out validation study

Older adults with sepsis have high mortality, but whether circulating immune-inflammatory biomarkers improve prediction beyond routine clinical information across hospitals is uncertain. We analysed 816 patients aged ≥ 60 years from a prospectively assembled multicentre cohort at...