Xiangyu Zhang

Preoperative C-Reactive Protein–Albumin–Lymphocyte Index and Related Clinical Factors Associated With Postoperative Complications Following Cholecystectomy in Acute Cholecystitis: A Retrospective Study

AIM: Laparoscopic cholecystectomy (LC) is the primary treatment for acute cholecystitis (AC), although various postoperative complications may still occur. Inflammatory composite indices have gained increasing attention in surgical risk assessment; among them, the C-reactive prot...

Gut microbiota-driven hippuric acid hydrolysis promotes pancreatic tumorigenesis by suppressing NK cell activity

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by a lack of effective early detection, profoundly immunosuppressive microenvironment, and poor responsiveness to current therapies. Emerging evidence suggests that gut microbiota a...