Xiangqiong Wang

Disrupting TERT-USP7 interaction to induces telomere-dependent senescence in hepatocellular carcinoma via mannose metabolism modulation

Abstract Induction of cellular senescence is an emerging therapeutic strategy for hepatocellular carcinoma (HCC) that exhibits inherent limited responsiveness to targeted therapies. However, the existing therapeutic methodologies for senescence induction predominantly depend on n...