Xianghuai Xu

Central SP/NK-1 signalling mediate cold-aggravated cough hypersensitivity in guinea pigs

Research question Cold exposure commonly worsens chronic cough, but mechanisms linking peripheral cold sensing to central cough hypersensitivity remain unclear. We examined whether cutaneous transient receptor potential ankyrin 1 (TRPA1) signalling contributes to cold-aggravated...

The landscape and plasticity of transposable element expression in an adult stem cell of high physiological and clinical significance

Abstract Transposable elements (TEs) contribute to diverse aspects of stem cell biology, particularly in germline and pluripotent stem cells, which typically exhibit more open chromatin. In human adult stem cells (ASCs), however, a comprehensive framework describing the landscape...