Xiang Li

MonoXtract: A Deep Learning Framework for Extracting Transmembrane Protein Dynamics from Single-Color Single-Molecule Imaging

Abstract Single-color fluorescence-based single-molecule techniques enable label-efficient probing of membrane-associated biomolecular dynamics. However, extracting reliable kinetic information is challenging due to signal heterogeneity, noise and the absence of reference channel...

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

ABSTRACT Diabetic foot ulcers are a major complication of diabetes characterized by persistent inflammation and impaired tissue repair, in part driven by aberrant activation of the cGAS‐STING innate immune pathway. Precision immunomodulation in the protease‐rich wound microenviro...