Xian Zhang

A microbiota–substrate–metabolite–target network suggests AKT1-associated links between gut microbiota-derived metabolites and osteoporosis

OBJECTIVE: To build a computational, hypothesis-generating framework that links gut microbiota-related metabolites with osteoporosis (OP) while retaining upstream microbial source and substrate information, and to prioritize candidate host targets, pathways, and modules for subse...