Wolfram Ruf

Lysed erythrocyte membranes metabolically prime endothelial cells for angiogenesis

Endothelial dysfunction is a hallmark of pathological angiogenesis and associated with erythrocyte extravasation and lysis. Whether mediators released from lysed erythrocytes instruct endothelial cells (ECs) for new vessel formation is unknown. Here, we show that the membrane fra...