Witsanu Yortchan

Coarse-graining analysis for non-invasive, label-free, and quantitative evaluation of undulating motion in cultured oral mucosa epithelial cell sheets

Background Cultured oral mucosa epithelial cell sheets (COMECS) represent a promising therapeutic approach for epithelial repair, such as corneal reconstruction or esophageal mucosa defects; however, current quality assessment methods are largely invasive and destructive. Althoug...

Epithelial integration in tissue-engineered oral mucosa using RGDTFI-presenting micropatterned collagen scaffolds

Objective To determine whether presentation of the integrin αvβ3/αvβ5-binding peptide motif RGDTFI on micropatterned collagen scaffolds improves epithelial coverage and stabilizes the epithelial–scaffold interface during fabrication of tissue-engineered oral mucosa (TEOM). Method...