William A. Nix

Advanced molecular poliovirus diagnostics across multiple real-time PCR platforms with locked nucleic acids and primer overhangs

This study details the development and validation of five real-time RT-PCR assays for the intratypic differentiation (ITD) of polioviruses and the discrimination of vaccine-derived polioviruses (VDPVs) utilizing locked nucleic acid (LNA) technology and primer overhangs. Updated a...