William A. Goddard

Enantioselective Reactions of Palladium Enolate Intermediates: Beyond Allylic Alkylation

Conspectus The enantioselective Pd-catalyzed allylic alkylation reaction has proven to be an incredibly powerful and versatile methodology for the construction of stereoenriched building blocks bearing all-carbon quaternary centers. We have contributed to this field by investigat...

BioForge: A Fast and Safe Macromolecular Structure Preparation Library in Rust

Abstract Summary BioForge is the first macromolecular structure preparation library for Rust, complementing sequence-analysis libraries such as Rust-Bio with cleaning, geometry-based missing-atom repair, protonation, and solvation as a force-field-agnostic preprocessing stage. Ac...