Wesley Chu

BaeR, EvgA and CpxR Differentially Regulate the Expression of acrD in Escherichia coli K-12 but Increased acrD Transcription Alone Does Not Demonstrate a Substantial Increase in Adaptive Resistance Against Kanamycin

Escherichia coli K-12 possesses the transmembrane AcrAD-TolC multidrug efflux complex. This pump is involved in the efflux of a variety of antibiotics, as well as amphipathic compounds. Studies suggest that the pretreatment of E. coli K-12 with kanamycin resulted in adaptive resi...