Wenjing Zhang

Primary Cardiac Angiosarcoma Initially Presenting with Sick Sinus Syndrome and Pericardial Effusion: A Case Report

Abstract Background Primary cardiac angiosarcoma is a rare and highly aggressive malignancy whose clinical presentation is primarily driven by local invasion and metastatic dissemination. Its rapid progression and frequent diagnostic delay contribute to a markedly poor prognosis....

Interpretable distillation reveals that deep learning splicing models suffer from pervasive confounders and blind spots

BACKGROUND: Predicting RNA splicing from genomic sequence is a crucial task for understanding gene regulation and interpreting genetic variation. Recent deep learning advancements have led to splicing prediction algorithms that achieve state-of-the-art performance compared to ear...