Wenchao Xia

Single-cell and bulk RNA sequencing demonstrate the critical function of the regulatory T cell-associated gene SIRPG in the prognosis and tumor microenvironment of esophageal squamous cell carcinoma

Immunosuppression by regulatory T cells (Tregs) significantly contributes to poor prognosis of esophageal squamous cell carcinoma (ESCC), although the specific regulatory genes and mechanisms involved are not well understood. We analyzed single-cell RNA sequencing and bulk transc...