Weiqiang Zhang

PPM-Level Palladium-Catalyzed Sonogashira Coupling Promoted by Fe3(CO)12 and α,β-Ynone Ligands

The development of sustainable cross-coupling methodologies that drastically reduce reliance on precious metals represents a central challenge in modern synthetic chemistry. Here we report a synergistic Pd/Fe bimetallic catalytic system for Sonogashira coupling that operates at a...