Weilv Xu

PEDV evades host immunity through reciprocal stabilization of PLP2 and GSDMD-CT

Abstract GSDMD-mediated pyroptosis is a critical component of the host innate immune defense against viral infection. While the pyroptosis-executing N-terminal domain of GSDMD (GSDMD-NT) has been extensively investigated, the role of the C-terminal domain (GSDMD-CT) remains large...