Weijian Huang

Comparative analysis of TP53 gene in Tupaia belangeri subspecies ( Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis ) and identification of mutations in spontaneous tumor cases

The tree shrew (Tupaia belangeri) is an emerging animal model for human diseases, yet the status of the critical tumor suppressor TP53 in its subspecies and spontaneous tumors is unknown. We sequenced the entire TP53 coding region from two subspecies, T. b. yaoshanensis and T. b....