Weijian Chen

Organ-Specific Toxicity of Lynestrenol in Mandarin Fish: Hepatic Metabolic Collapse versus Ovarian Resilience through Efflux Transporter Activation

Abstract Lynestrenol (LYN), a fourth-generation synthetic progestin whose active metabolite norethisterone is frequently detected in aquatic environments, poses potential risks to fish. Using integrated multi-omics, enzymology, and histopathology, we investigated the organ-specif...