Wei Shi

Mechanism of HO-1 in alleviating sepsis-associated acute kidney injury via regulating mitochondrial proteostasis and targeted intervention with DNA nanomaterials

Sepsis-associated acute kidney injury (S-AKI) is a major driver of systemic mortality and chronic renal dysfunction, yet effective mechanism-based interventions are lacking. Clinical analysis revealed significant oxidative stress imbalance in patients with S-AKI, characterized by...