Wei Hao

Curcumin Enhances the Sensitivity of 5-fluorouracil-resistant Colon Cancer Cells to 5-fluorouracil Through a Ferroptosis-related Mechanism: A Network Pharmacology and In Vitro Study

Background Colorectal cancer (CRC) is a common and deadly malignancy. Although 5-fluorouracil (5-FU) continues to be a standard therapeutic agent for CRC, the development of resistance substantially compromises its clinical effectiveness. Curcumin, a natural polyphenol, has shown...