Wanzhe Zhang

IL-2-mediated Treg cells recruitment regulates neuroimmune crosstalk to promote hippocampal neurogenesis in depressive mice

Major depressive disorder (MDD) is a prevalent and debilitating neuropsychiatric disorder characterized by severe neuroinflammation and impaired hippocampal neurogenesis, yet effective clinical treatments remain limited. Accumulating evidence indicates that adaptive immune dysfun...