Wanyang Chen

Single-cell transcriptomics and machine learning characterize LTA4H-linked lipid metabolism and inflammatory signatures in the knee osteoarthritis IPFP/synovium compartment

Knee osteoarthritis (KOA) is a whole-joint disease characterized by inflammation, immune dysregulation, and metabolic imbalance. To define lipid metabolism-related transcriptional heterogeneity within the infrapatellar fat pad (IPFP)/synovium compartment, we integrated publicly a...