Volker Siffrin

Astrocytic EAAT ‐2 Upregulation Supports Neuro‐Axonal Homeostasis in Chronic Inflammatory CNS Lesions

ABSTRACT Neuronal loss in multiple sclerosis (MS) is a key factor in the progression of disability. Axonal degeneration within MS lesions is central to progressive MS pathology, yet its mechanisms are not fully understood. Excess extracellular l‐glutamate (GLUT) is neurotoxic due...