Vladimir Mitev

A methodological framework for real-world performance studies of clinical variant classification platforms at early organizational stages

Automated platforms that classify sequence variants under the American College of Medical Genetics and Genomics/Association for Molecular Pathology (ACMG/AMP) framework are increasingly used in rare-disease genomics, yet methodology for characterizing their performance at an earl...

Noodle: Semantic Biomedical Literature Discovery and Navigable Publication Graph

Noodle is a free, public, read-only web application for semantic discovery and navigation of biomedical literature. It integrates publication metadata and source-linked context from PubMed, Europe PMC, and OpenAlex while preserving those services as the authoritative sources. Noo...

Noodle: Semantic Biomedical Literature Discovery and Navigable Publication Graph

Noodle is a free, public, read-only web application for semantic discovery and navigation of biomedical literature. It integrates publication metadata and source-linked context from PubMed, Europe PMC, and OpenAlex while preserving those services as the authoritative sources. Noo...

Robustness and cross-cohort concordance of developmental regulons in endometrial carcinoma

Claims about regulatory differences among endometrial carcinoma molecular classes must distinguish association, target-set robustness, and cross-cohort transportability. We evaluated a fetal Müllerian epithelial module and 20 prespecified developmental transcription-factor regulo...