Victor R. DeFilippis

Evaluation of a Zika virus-like particle-based vaccine in a highly penetrant non-human primate model of congenital infection

Zika virus (ZIKV) is an arthropod-borne Orthoflavivirus that caused a major outbreak in Central and South America in 2015–16. During that outbreak, ZIKV infection during pregnancy was associated with high rates of adverse outcomes, including miscarriage and a spectrum of neurolog...