Varadan Sevilimedu

De-escalation of Axillary Surgery in Early Breast Cancer

OBJECTIVE: To prospectively evaluate how often axillary staging can successfully be omitted in postmenopausal HR+/HER2- patients. BACKGROUND: Three randomized trials showed no difference in recurrence or survival outcomes with omission of sentinel lymph node biopsy (SLNB) in cT1-...

Axillary Nodal Upstaging in cT1N0 Invasive Lobular Carcinoma

OBJECTIVE: To determine whether sentinel lymph node biopsy (SLNB) omission is applicable to stage 1 invasive lobular breast cancer (ILC). BACKGROUND: The SOUND and INSEMA randomized controlled trials demonstrated that SLNB omission is noninferior to performing SLNB in early-stage...