Utta Berchner-Pfannschmidt

Proteogenomic Analysis of HDAC4 and HDAC5 in Uveal Melanoma

Abstract Uveal melanoma (UM) is a rare but aggressive cancer arising from cells of the uveal tract that is highly resistant to therapy once it has metastasized. In drug screening experiments, we identified a high sensitivity of primary UM cell lines to the pan-histone deacetylase...