Tzu‐Ming Liu

Resolving the Sensitivity–Specificity Trade‐Off in Fluorescent Probes via a Tandem‐Activatable Shielding Strategy

ABSTRACT For precise tumor diagnosis, the intrinsic trade‐off between sensitivity and specificity in fluorescent probes remains a longstanding bottleneck, underscoring an urgent need for strategies to break this fundamental constraint. To address the specificity limitation, we ex...

Resolving the Sensitivity–Specificity Trade‐Off in Fluorescent Probes via a Tandem‐Activatable Shielding Strategy

ABSTRACT For precise tumor diagnosis, the intrinsic trade‐off between sensitivity and specificity in fluorescent probes remains a longstanding bottleneck, underscoring an urgent need for strategies to break this fundamental constraint. To address the specificity limitation, we ex...

Harnessing Differential Restriction of Molecular Motion within a Single Fluorophore for Versatile Bioimaging

Abstract Numerous studies have highlighted how differently restricted molecular motions within molecular packing can profoundly alter the photophysical properties of fluorophores. However, most investigations remain confined to solid-state luminescence polymorphism, while extendi...