Turki Turki

Interpretable integration of CITE-seq RNA and ADT profiles without explicit modality-weight tuning via tensor decomposition-based unsupervised feature extraction

CITE-seq jointly profiles cellular transcripts and surface proteins, but RNA and ADT modalities differ markedly in dimensionality, sparsity, and noise characteristics. We applied tensor-decomposition-based unsupervised feature extraction to paired CITE-seq data by constructing a...