Trinath Ghosh

Transcriptomic trajectory of hepatocyte ballooning reveals a lipotoxic point of no return and initiates oncogenic regulatory rewiring in MASLD

Background Hepatocyte ballooning is a defining histological marker of progressive steatohepatitis, but its molecular basis remains poorly defined. Objective To identify a molecular signature and mechanistic trajectory underlying hepatocyte ballooning across the MASLD-to-hepatocel...