Torben Hansen

Evaluating the consequences of childhood adiposity on the human plasma proteome at four timepoints across the lifecourse

Abstract Applying a lifecourse approach using human genetic data, we evaluate the effect of childhood adiposity on the circulating proteome using measurements taken at four key life stages. Using lifecourse Mendelian randomization, we find genetically predicted childhood adiposit...

Predicting future risk of type 1 and type 2 diabetes after gestational diabetes mellitus using polygenic scores: a cohort study

AIMS/HYPOTHESIS: Women with previous gestational diabetes mellitus (GDM) have an increased risk of developing both type 1 and type 2 diabetes. However, predicting the risk on a personal level is challenging. Polygenic scores (PGSs), which capture an individual's genetic susceptib...