Tomohiko Nagasawa

Neuroimmune buffering reserve at the neurovascular unit: a CLDN5- and microglia-centred view of recurrent peripheral inflammation

Abstract Question Recurrent peripheral inflammatory flares are rarely framed as longitudinal stress tests of the neuroimmune interface. Within the neurovascular unit (NVU), endothelial cells, pericytes, astrocytic endfeet, basement membranes, perivascular cells, and glia jointly...