Tomasz Maciej Stępniewski

The GPCRVP score reliably predicts the impact of GLP1R human variants on receptor function

Abstract Aims/hypothesis The glucagon-like peptide-1 receptor (GLP1R) is a key regulator of glucose homeostasis and body weight, and a major therapeutic target for type 2 diabetes and obesity. Individual disease risk and response to treatments may vary widely depending on the pre...