Tomas Fiala

Lysine Oxidation by LOXL2 in Single Strands Versus Triple Helices: Implications for Collagen‐Related Diseases

ABSTRACT Collagen cross‐linking is essential for the structural integrity of the extracellular matrix. In several pathological conditions, the triple‐helical core of collagen is disrupted, and proline‐rich single strands occur. Lysyl oxidases (LOXs), enzymes that initiate cross‐l...