Todd Kitten

Complete genome sequences of 38 Streptococcus sanguinis human-associated isolates

ABSTRACT We report the complete genome sequences of 38 Streptococcus sanguinis genomes, isolated from human oral and endocarditis-associated samples. These genomes are each comprised of a single chromosome that ranges from approximately 2.29 to 2.48 Mb in length, with an average...

A genome-wide in vivo screen reveals fitness pathways required for streptococcal infective endocarditis

Abstract Infective endocarditis (IE) is a life-threatening disease most often caused by blood-borne bacteria that infect previously damaged cardiac tissue. Despite the importance of this disease, the genetic basis for IE virulence remains poorly defined. Here, we present the firs...